Journal of Pharmaceutical Sciences and Research

Background: The angle of inclination (neck-shaft angle) and femoral neck length are critical morphometric parameters of the proximal femur that determine hip biomechanics, fracture risk, and implant design requirements Objective: To determine the angle of inclination and neck length of dry femur and to analyze side differences, correlations, and it's clinical relevance. Methods: A cross-sectional observational study was conducted on 50 dry adult human femur (25 right, 25 left) obtained from the Department of Anatomy, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Bemina, Srinagar. The angle of inclination was measured using a standard osteometric board and goniometer, while neck length was measured with a sliding caliper. Data were analyzed using SPSS version 23.0 for descriptive statistics, independent t-tests, and Pearson correlation. Results: The overall mean angle of inclination was 128.42° ± 4.18° (range 119°–139°). The mean neck length was 29.6 ± 2.8 mm (range 24–36 mm). Right-sided femur showed a mean angle of 129.18° ± 4.42° and neck length of 30.2 ± 2.6 mm, while left-sided femur showed a mean angle of 127.66° ± 3.82° and neck length of 29.0 ± 2.9 mm. No statistically significant side differences were observed for either parameter (p > 0.05). A statistically significant positive correlation was found between the angle of inclination and neck length (r = 0.412, p = 0.003). Conclusion: The mean angle of inclination and neck length in the present sample are consistent with South Asian reference ranges but lower than Western and East Asian standards. The significant positive correlation between these parameters supports integrated proximal femoral architecture. Population-specific implant designs are recommended for optimal orthopedic outcomes in this geographic region